Manejo de síntomas neuropsiquiátricos en pacientes con demencia en cuidados paliativos

Autores/as

Palabras clave:

Síntomas neuropsiquiátricos, agitación psicomotora, cuidados paliativos, delirium, trastornos neurocognitivos

Resumen

El tratamiento de los síntomas neuropsiquiátricos en cuidados paliativos influye directamente en la calidad de vida del paciente. El objetivo del estudio es describir las recomendaciones actuales en el manejo de los síntomas neuropsiquiátricos en cuidados paliativos. Se tomaron guías clínicas de los últimos 10 años, en bases de datos como Pubmed, TripDatabase y Google académico. Con una estrategia basada en términos Mesh/DecS y operadores booleanos. Se siguió la metodología PRISMA. Se analizaron 16 guías de prácticas clínicas sobre el manejo de los síntomas neuropsiquiátricos, en las que se observó que existen dos enfoques de tratamiento: no farmacológico y farmacológico. El primero incluye control de factores como deshidratación, dolor, hiponatremia o hipoglucemia, además del control del ambiente, exposición a la luz solar, y varias estrategias para lograr su relajación. El abordaje farmacológico implica usar psicotrópicos como el haloperidol, junto con benzodiacepinas, si no hay respuesta adecuada con el manejo no farmacológico. Se evidenció que el manejo adecuado de los síntomas neuropsiquiátricos en cuidados paliativos se basa en una atención multidimensional que no solo se centra en la reducción de los síntomas físicos, sino que también considera el bienestar emocional y social del paciente y su familia.

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Biografía del autor/a

Diego Raúl Bonifaz-Díaz, Universidad Iberoamericana. Ecuador.

 

 

Citas

Anneser, J., Arenz, V., & Borasio, G. D. (2018). Neurological Symptoms in Palliative Care Patients. Frontiers in Neurology, 9(2), 145–159. https://doi.org/10.3389/fneur.2018.00275

Britt, K. C., Richards, K. C., Kesler, S., Acton, G., Hamilton, J., & Radhakrishnan, K. (2023). The Association of Private Prayer with Neuropsychiatric Symptoms, Cognition, and Sleep Disturbances in Persons with Dementia (Sci255). Journal of Pain and Symptom Management, 65(5), 670–681. https://doi.org/10.1016/j.jpainsymman.2023.02.305

Canadian Coalition for Seniors’ Mental Health. (2024). Canadian Clinical Practice Guidelines for Assessing and Managing Behavioural and Psychological Symptoms of Dementia (BPSD). https://ccsmh.ca/wp-content/uploads/2024/03/CCSMH-BPSD-Clinical-Guidelines_FINAL_March-2024.pdf

Chan, L., & Corso, G. (2024). Pharmacological and non-pharmacological prevention and management of delirium in critically ill and palliative patients in the inpatient setting: a review. Frontiers in Medicine, 11(17), 11–19. https://doi.org/10.3389/fmed.2024.1403842

Cummings, J., Lanctot, K., Grossberg, G., & Ballard, C. (2024). Progress in Pharmacologic Management of Neuropsychiatric Syndromes in Neurodegenerative Disorders. JAMA Neurology, 81(6), 645–652. https://doi.org/10.1001/jamaneurol.2024.0586

Ecuador. Ministerio de Salud Pública. (2014). Cuidados paliativos. Guía de Práctica Clínica. http://hgona.gob.ec/index.php/gpc-cuidados-paliativos-completa/

García, V., De Hoyos, M., Ariza, G., Delgado, R., García, P., Hernández, E., De Haro-de Torres, J., & Del Cura-González, I. (2022). Neuropsychiatric symptoms and subsyndromes in patients with different stages of dementia in primary care follow-up (NeDEM project): a cross-sectional study. BMC Geriatrics, 22(1), 71–83. https://doi.org/10.1186/s12877-022-02762-9

Grassi, L., Caruso, R., Riba, M. B., Lloyd-Williams, M., Kissane, D., Rodin, G., McFarland, D., Campos-Ródenas, R., Zachariae, R., Santini, D., & Ripamonti, C. I. (2023). Anxiety and depression in adult cancer patients: ESMO Clinical Practice Guideline. ESMO Open, 8(2). https://doi.org/10.1016/j.esmoop.2023.101155

Greater Manchester Medicines Management, & Group. (2022). Palliative care pain & symptom control guidelines for adults for staff providing generalist palliative care. https://www.england.nhs.uk/north-west/wp-content/uploads/sites/48/2020/01/Palliative-Care-Pain-and-Symptom-Control-Guidelines.pdf

Johanna Briggs Institute. (2020). Critical Appraisal Tool. https://jbi.global/critical-appraisal-tools

Kawashima, N., Yokomichi, N., Morita, T., Yabuki, R., Hisanaga, T., Imai, K., Hirose, Y., Shimokawa, M., Miwa, S., Yamauchi, T., Okamoto, S., & Satomi, E. (2024). Comparison of Pharmacological Treatments for Agitated Delirium in the Last Days of Life. Journal of Pain and Symptom Management, 67(5), 441–452. https://doi.org/10.1016/j.jpainsymman.2024.02.008

Lorusso, L. N., & Bosch, S. J. (2018). Impact of Multisensory Environments on Behavior for People With Dementia: A Systematic Literature Review. The Gerontologist, 58(3), 168–179. https://doi.org/10.1093/GERONT/GNW168

Maters, J., van der Steen, J. T., de Vugt, M. E., Bakker, C., & Koopmans, R. T. C. M. (2024). Palliative Care in Nursing Home Residents with Young-Onset Dementia: Professional and Family Caregiver Perspectives. Journal of Alzheimer’s Disease, 97(2), 573–586. https://doi.org/10.3233/JAD-230486

National Cancer Grid. (2021). NCG Palliative Care Guidelines – End of Life Care. https://www.ncgindia.org/assets/palliative-care-guidelines/approach-to-managing-end-of-life-care.pdf

National Coalition for Hospice and Palliative Care. (2018). Clinical Practice Guidelines for Quality Palliative Care, 4th edition. National Coalition for Hospice and Palliative Care.

National Institute for Health and Excellence. (2015). Care of dying adults in the last days of life. https://www.ncbi.nlm.nih.gov/books/NBK338140/

North East and North Cumbria. (2021). Palliative and End of Life Care Symptom Control Guidelines for cancer and non-cancer patients. https://northerncanceralliance.nhs.uk/wp-content/uploads/2022/06/20220615-Palliative-and-End-of-Life-Care-Guidelines-2021-DOWNLOAD.pdf

North West Coast Clinical Network. (2024). Palliative Care Guidelines in Dementia 3rd Edition. https://www.england.nhs.uk/north-west/wp-content/uploads/sites/48/2024/11/Palliative-Care-Guidelines-in-Dementia-3rd-ed-Nov-2024-PDF-VERSION-1.pdf

Northern England Clinical Networks. (2016). Palliative and End of Life Care Guidelines Symptom control for cancer and non-cancer patients. https://www.northerncanceralliance.nhs.uk/wp-content/uploads/2018/11/NECNXPALLIATIVEXCAREX2016-1.pdf

Page, M., McKenzie, J., Bossuyt, P., Boutron, I., Hoffmann, T., Mulrow, C. D., Shamseer, L., Tetzlaff, J., Akl, E., Brennan, S., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., & Moher, D. (2021). The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ, 2(4), 71–75. https://doi.org/10.1136/bmj.n71

Parker, D., Lewis, J., & Gourlay, K. (2016). Palliative Care and dementia. https://www.dementia.org.au/sites/default/files/2024-02/DA-Numbered-Publication-43-Palliative-care-and-dementia.pdf

Pless, A., Ware, D., Saggu, S., Rehman, H., Morgan, J., & Wang, Q. (2023). Understanding neuropsychiatric symptoms in Alzheimer’s disease: challenges and advances in diagnosis and treatment. Frontiers in Neuroscience, 17, 1263771. https://doi.org/10.3389/FNINS.2023.1263771/BIBTEX

Radbruch, L., De Lima, L., Knaul, F., Wenk, R., Ali, Z., Bhatnaghar, S., Blanchard, C., Bruera, E., Buitrago, R., Burla, C., Callaway, M., Munyoro, E. C., Centeno, C., Cleary, J., Connor, S., Davaasuren, O., Downing, J., Foley, K., Goh, C., & Pastrana, T. (2020). Redefining Palliative Care—A New Consensus-Based Definition. Journal of Pain and Symptom Management, 60(4), 754–764. https://doi.org/10.1016/j.jpainsymman.2020.04.027

Rezaei, F., Reamazannezhad, N., Douki, M., Shayadeh, F., Nejati, E., & Ahmadian, Z. (2020). Nursing care (palliative medicine) in patients with neuropsychiatric disorders. Journal of Family Medicine and Primary Care, 9(1), 25–30. https://doi.org/10.4103/jfmpc.jfmpc_701_19

Sano, M., Cummings, J., Auer, S., Bergh, S., Fischer, C. E., Gerritsen, D., Grossberg, G., Ismail, Z., Lanctôt, K., Lapid, M. I., Mintzer, J., Palm, R., Rosenberg, P. B., Splaine, M., Zhong, K., & Zhu, C. W. (2024). Agitation in cognitive disorders: Progress in the International Psychogeriatric Association consensus clinical and research definition. International Psychogeriatrics, 36(4), 238–250. https://doi.org/10.1017/S1041610222001041

Scottish Intercollegiate Guidelines Network. (2023). Assessment, diagnosis, care and support for people with dementia and their careers 2023. https://www.sign.ac.uk/our-guidelines/assessment-diagnosis-care-and-support-for-people-with-dementia-and-their-carers/

Shin, J., Chang, Y. J., Park, S.-J., Choi, J. Y., Kim, S.-H., Choi, Y. S., Kim, N. H., Yum, H.-K., Nam, E. M., Park, M. H., Moon, N., Moon, J. Y., Kang, H.-T., Kang, J. H., Park, J.-M., Lee, C.-W., Kim, S.-Y., Lee, E. J., Koh, S.-J., & Shim, J. Y. (2020). Clinical Practice Guideline for Care in the Last Days of Life. The Korean Journal of Hospice and Palliative Care, 23(3), 103–113. https://doi.org/10.14475/kjhpc.2020.23.3.103

Walsh, S. C., Murphy, E., Devane, D., Sampson, E. L., Connolly, S., Carney, P., & O’Shea, E. (2021). Palliative care interventions in advanced dementia. Cochrane Database of Systematic Reviews, (9), 2–17. https://doi.org/10.1002/14651858.CD011513.pub3

Wendrich-van Dael, A., Bunn, F., Lynch, J., Pivodic, L., Van den Block, L., & Goodman, C. (2020). Advance care planning for people living with dementia: An umbrella review of effectiveness and experiences. International Journal of Nursing Studies, 107(2), 103–115. https://doi.org/10.1016/j.ijnurstu.2020.103576

Wessex Palliative Physicians. (2019). The Palliative Care Handbook. https://www.ruh.nhs.uk/for_clinicians/departments_ruh/palliative_care/documents/palliative_care_handbook.pdf

World Health Organzation. (2020). Palliative care. https://www.who.int/news-room/fact-sheets/detail/palliative-care

Yorkshire and the Humber Health and Care Partnership. (2024). A Guide to Symptom Management in Palliative Care. https://humberandnorthyorkshire.org.uk/wp-content/uploads/2024/05/A-Guide-to-Symptom-Management-in-Palliative-Care-v8-Approved-by-HNY-IPMOC-February-2024.pdf

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Publicado

2025-01-01

Cómo citar

Escobar-Morillo, A. L., & Bonifaz-Díaz, D. R. (2025). Manejo de síntomas neuropsiquiátricos en pacientes con demencia en cuidados paliativos. Revista UGC, 3(1), 191–201. Recuperado a partir de https://universidadugc.edu.mx/ojs/index.php/rugc/article/view/87