Influence of emerging technologies applied to the prognosis of traumatic brain injury

Authors

Keywords:

Clinical prediction, neurological prognosis, predictive models, clinical decision making, emerging technologies

Abstract

Intracranial traumatic injuries, such as acute subdural hematoma, cerebral contusion, and post-traumatic subarachnoid hemorrhage, have become a public health problem due to their high morbidity and mortality rates and the complexity of their clinical management. Within this context, artificial intelligence has emerged as an innovative alternative to optimize the prediction of clinical severity and support timely medical decision-making. Therefore, this study aimed to analyze the current scientific evidence regarding artificial intelligence models designed to predict clinical severity in patients with acute subdural hematoma, cerebral contusion, and post-traumatic subarachnoid hemorrhage. A descriptive literature review was conducted using international biomedical databases. The review identified that machine learning and learning models have demonstrated high levels of predictive accuracy, particularly in estimating adverse clinical outcomes, risk stratification, and supporting early diagnosis, although methodological variability exists among studies. It was concluded that the analyzed evidence indicated that artificial intelligence has proven to be a promising tool for predicting clinical severity in traumatic brain injury. However, ethical, technical, and operational limitations have persisted, requiring methodological standardization and strengthening of future clinical validation. Therefore, it has been considered that future lines of research should focus on developing explainable models, expanding heterogeneous databases, and the ethical and regulatory integration of these technologies.

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References

Andishgar, A., Rismani, M., Bazmi, S., Mohammadi, Z., Hooshmandi, S., Kian, B., Niakan, A., Taheri, R., Khalili, H., & Alizadehsani, R. (2025). Developing practical machine learning survival models to identify high-risk patients for in-hospital mortality following traumatic brain injury. Scientific Reports, 15(5913). https://www.nature.com/articles/s41598-025-89574-0

Fan, X., Xu, J., Ye, R., Zhang, Q., & Wang, Y. (2025). Retrospective cohort study based on the MIMIC-IV database: Analysis of factors influencing all-cause mortality at 30 days, 90 days, 1 year, and 3 years in patients with different types of stroke. Frontiers in Neurology, 15. https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1516079/full

García-Mc Collins, M. del P. (2025). Innovación en la práctica de enfermería: implementando nuevas tecnologías y enfoques para mejorar la atención al paciente. Sophia Research Review, 2(3), 15-19. https://doi.org/10.64092/388she15

Ge, S., Chen, J., Wang, W., Zhang, L.-B., Teng, Y., Yang, C., Wang, H., Tao, Y., Chen, Z., Li, R., Niu, Y., Zuo, C., & Tan, L. (2024). Predicting who has delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage using machine learning approach: A multicenter, retrospective cohort study. BMC Neurology, 24(177). https://link.springer.com/article/10.1186/s12883-024-03630-2

Gong, B., Khalvati, F., Ertl-Wagner, B. B., & Patlas, M. N. (2025). Artificial intelligence in emergency neuroradiology: Current applications and perspectives. Diagnostic and Interventional Imaging, 106(4), 135–142. https://www.sciencedirect.com/science/article/pii/S2211568424002572

Guranda, A., Richter, A., Wach, J., Güresir, E., & Vychopen, M. (2025). PROMISE: Prognostic Radiomic Outcome Measurement in acute subdural hematoma evacuation post-craniotomy. Brain Sciences, 15(1), 58. https://www.mdpi.com/2076-3425/15/1/58

Huang, C.-C., Chiang, H.-F., Hsieh, C.-C., Zhu, B.-R., Wu, W.-J., & Shaw, J.-S. (2025). Impact of dataset size on 3D CNN performance in intracranial hemorrhage classification. Diagnostics, 15(2), 216. https://www.mdpi.com/2075-4418/15/2/216

Karabacak, M., & Margetis, K. (2024). Machine learning–driven prognostication in traumatic subdural hematoma: Development of a predictive web application. Neurosurgery Practice, 5(1), 1–13. https://journals.lww.com/neurosurgpraconline/fulltext/2024/03000/machine_learning_driven_prognostication_in.12.aspx

Khalili, H., Rismani, M., Nematollahi, M. A., Masoudi, M. S., Asadollahi, A., Taheri, R., Pourmontaseri, H., Valibeygi, A., Roshanzamir, M., Alizadehsani, R., Niakan, A., Andishgar, A., Islam, S. M. S., & Acharya, U. R. (2023). Prognosis prediction in traumatic brain injury patients using machine learning algorithms. Scientific Reports, 13(960), 1–15. https://doi.org/10.1038/s41598-023-28188-w

Khan, M. M., Chowdhury, A. T., Sumon, M. S. I., Maheboob, S. N., Ali, A., Thabet, A. N., Al-Rumaihi, G., Belkhair, S., AlSulaiti, G., Ayyad, A., Shah, N., Hasan, A., Pedersen, S., & Chowdhury, M. E. H. (2025). Multi-class subarachnoid hemorrhage severity prediction: Addressing challenges in predicting rare outcomes. Neurosurgical Review, 48(554), 1–15. https://link.springer.com/article/10.1007/s10143-025-03678-9

Khaniyev, T., Cekic, E., Nisa Gecici, N., Can, S., Ata, N., Ulgu, M. M., Birinci, S., Isikay, A. I., Bakir, A., Arat, A., & Hanalioglu, S. (2025). Predicting mortality in subarachnoid hemorrhage patients using big data and machine learning: A nationwide study in Türkiye. Journal of Clinical Medicine, 14(4), 1144. https://www.mdpi.com/2077-0383/14/4/1144

Kumar, S., Ramprasath, J., Kalpana, V., Rajagopal, M., S, M., & Gupta, R. (2025). Integrating brain-inspired computation with big-data analytics for advanced diagnostics in neuroradiology. Neuroscience Informatics, 5(2), 1–11. https://www.sciencedirect.com/science/article/pii/S2772528625000172

Liu, H., Su, Y., Peng, M., Zhang, D., Wang, Q., Zhang, M., Ge, R., Xu, H., Chang, J., & Shao, X. (2024). Prediction of prognosis in patients with cerebral contusions based on machine learning. Scientific Reports, 14(31993), 1–12. https://www.nature.com/articles/s41598-024-83481-6

Mohammadzadeh, I., Hajikarimloo, B., Eini, P., Niroomand, B., Mohammadzadeh, S., Habibi, M. A., Babak, Z. M., & Aliaghaei, A. (2025). Can machine learning be a reliable tool for predicting hematoma progression following traumatic brain injury? A systematic review and meta-analysis. Neuroradiology, 67(7), 1733–1749. https://doi.org/10.1007/s00234-025-03657-3

Moriya, M., Karako, K., Miyazaki, S., Minakata, S., Satoh, S., Abe, Y., Suzuki, S., Miyazato, S., & Takara, H. (2025). Interpretable machine learning model for outcome prediction in patients with aneurysmatic subarachnoid hemorrhage. Critical Care, 29(36), 1–11. https://link.springer.com/article/10.1186/s13054-024-05245-y

Panda, S., Biswal, S. S., Rath, S. S., & Saxena, S. (2025). Chapter 11 - Traditional and advanced AI methods used in the area of neuro-oncology. Radiomics and Radiogenomics in Neuro-Oncology, 2(2025), 277–300. https://doi.org/10.1016/B978-0-443-18509-0.00008-6

Roy García, I. A., Paredes Manjarrez, C., Moreno Palacios, J., Rivas Ruiz, R., & Flores Pulido, A. A. (2023). Curvas ROC: Características generales y su uso en la práctica clínica. Revista Médica del Instituto Mexicano del Seguro Social, 61(Supl 3), S497–S502. https://revistamedica.imss.gob.mx/index.php/revista_medica/article/view/5074

Sánchez-Núñez, K. E. (2026). Sánchez-Núñez, K. E. (2026). Nursing Education in the Digital Age: SmartNurse as a Bridge to Innovation. Sophia Research Review, 3(1), 5-8. https://doi.org/10.64092/vafchy37

Shih, R. Y., Burns, J., Ajam, A. A., Broder, J. S., Chakraborty, S., Kendi, A. T., Lacy, M. E., Ledbetter, L. N., Lee, R. K., Liebeskind, D. S., Pollock, J. M., Prall, J. A., Ptak, T., Raksin, P. B., Shaines, M. D., Tsiouris, A. J., Utukuri, P. S., Wang, L. L., & Corey, A. S. (2021). ACR Appropriateness Criteria® Head Trauma: 2021 update. Journal of the American College of Radiology, 18(5, Supplement), S13–S36. https://doi.org/10.1016/j.jacr.2021.01.006

Tlalpachicatl Cruz, N., Pérez López, C. G., & Pérez López, C. I. (2024). Aula invertida en educación superior: Análisis de un curso de métodos de investigación en psicología educativa. Revista Iberoamericana de Educación, 95(1), 161–177. https://doi.org/10.35362/rie9516268

Torres Espin, A. (2025). Priorities towards precision neurotrauma: A methodological perspective. The Journal of Precision Medicine: Health and Disease, 3(October), 1–5. https://doi.org/10.1016/j.premed.2025.100022

Zade, A. P., Bhoge, S. S., Seth, N. H., & Phansopkar, P. (2023). Rehabilitation of traumatic acute subdural hematoma and subarachnoid hemorrhage: A case report. Cureus, 15(12), 1–9. https://pubmed.ncbi.nlm.nih.gov/38229824/

Published

2026-04-01

How to Cite

Acurio-Padilla, P. E., Guerreo-Rea, C. R., Huilca-Galarza, H. A., & Jaramillo-Aguilar, A. P. (2026). Influence of emerging technologies applied to the prognosis of traumatic brain injury. Revista UGC, 4(2), 53–59. Retrieved from https://universidadugc.edu.mx/ojs/index.php/rugc/article/view/340